B Medical Systems teams up with SEEDR to launch next generation of intelligent freeze-free vaccine carriers and transport boxes

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B Medical Systems and SEEDR are joining forces to bring to the market a new cold chain solution to help solve the global challenge of keeping vaccines safe and effective against extreme heat and freezing temperatures.

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  • Vaccine transport box

The Luxembourg- and US-based companies took on the challenge of developing a new range of intelligent Grade-A passive freeze-free technology. The new devices, under review by the World Health Organization’s (WHO) standards and safety division, promise to help protect millions of children from infectious diseases by ensuring potent vaccines in the remotest locations of the world.

“At B Medical Systems, we have been innovating reliable cold chain technologies for 35 years, not only for market solutions, but to first and foremost ensure every child a healthy life. Since 1979, when the WHO approached us to provide a solution to safely store and transport vaccines around the world, we have been driven by the ambition to continuously create medical devices that respond directly to the obstacles countries face to equitably safeguard their children’s health,” comments Luc Provost, CEO of B Medical Systems.

According to UNICEF, an estimated 19.9 million infants worldwide were not reached with routine immunization services in 2017.i As vaccines are temperature-sensitive, their transport requires a constant temperature between 2-8°C all the way from the manufacturer to the end-users, even when it comes to populations living in the remotest rural areas of the world. Insulated transport technologies help shield vaccines from damage caused by heat. Yet too much ice can cause them to freeze. Once exposed to sub-zero temperatures, approximately 85% of routine vaccines lose their potency and must be immediately discarded or risk vaccinating children with an ineffective, or worse, harmful antigen. Studies of cold chain performance show that between 75 and 100% of vaccine shipments are exposed to freezing temperatures.ii

The partnership between B Medical Systems and SEEDR will launch the next generation of intelligent vaccine carriers and transport boxes using new production technologies and materials. The new devices will prevent inadvertent vaccine freezing and help ensure every child is protected against vaccine-preventable diseases, answering the call to industry put out from Gavi, the Vaccine Alliance. Gavi spends over $1 billion a year to help countries vaccinate over 60 million children annually and has called for new cold chain technology to help countries keep pace with the massive increase in the value and quantity of vaccines.iii

“85% of low and middle-income countries have inadequate vaccine distribution systems, affecting millions of children each year. Clinical diagnostics and disease surveillance systems facing similar cold chain challenges affect tens of millions more. By combining the best in design, engineering, and manufacturing with insights and input from governments, logisticians, and healthcare providers in the field; the products of this collaboration will accelerate a step-change improvement in access to quality care at scale,” adds Michael Moreland, SEEDR’s founder.

SEEDR and B Medical Systems have already commenced work focused on the optimization, manufacturing, and commercialization of the new devices. Expected to be launched in early 2019, the new product family will not only provide Grade-A freeze protection, but also several other powerful new features to revolutionize the broader passive transport industry for a range of temperature-sensitive biologics, including blood and plasma, biological samples for diagnostics and surveillance, vaccines and other pharmaceuticals.

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